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Hindi Case Report
Acute Gastrointestinal Bleeding with Hypovolemic Shock Induced by Gastrointestinal Stromal Tumor Coincident with Neurofibromatosis Type 1: A Case Report
Gha Na Jo1, Kang Hong Lee2 and Byung Kyu Ahn2*
1Department of Surgery, Hanyang University Medical Center, Seoul, Korea
2Department of Surgery, Hanyang University College of Medicine, Seoul, Korea
- *Corresponding Author:
- Byung Kyu Ahn, MD, PhD
Address: Department of Surgery
Hanyang University College of Medicine 17 Haengdang-dong
Seongdong-ku, Seoul 133-792, Korea
Tel: +82-2-2290-8460
Fax: +82-2-2281-0224
E-mail: bkahn@hanyang.ac.kr
Received date: May 15, 2015; Accepted date: June 06, 2015; Published date: June 12, 2015
Citation: Na Jo G, Lee KH, Ahn BK (2015) Acute Gastrointestinal Bleeding with Hypovolemic Shock Induced by Gastrointestinal Stromal Tumor Coincident with Neurofibromatosis Type 1: A Case Report. J Gastrointest Dig Syst 5:299. doi:10.4172/2161-069X.1000299
Copyright: © 2015 Na Jo G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License; which permits unrestricted use; distribution; and reproduction in any medium; provided the original author and source are credited.
Abstract
We report a case of young patient diagnosed as Neurofibromatosis type 1 (NF-1) five years ago. A 42-year-old male was admitted due to sudden onset of gastrointestinal bleeding. Contrast enhanced computed tomography (CT) scan revealed a lobulating unenhanced mass, originating from the small bowel in the pelvic cavity. The patient developed a fulminant gastrointestinal hemorrhage and emergency operation was performed. On operation, multilobulated submucosal mass was observed on the serosal surface of proximal ileum and this tumor with hemorrhagic and cystic change was the source of bleeding. Histopathological examination revealed this tumor was 5.5 cm × 5 cm × 4 cm in size and small bowel gastrointestinal stromal tumor (GIST) with moderate risk malignant potential. Immunohistochemical examination showed that C-kit and CD34 were positive. In neurofibromatosis, GISTs are more frequent and we should pay attention to gastrointestinal manifestation in such patients.
