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Acute Upper Gastrointestinal Bleeding from Gastric Involvement of Chronic Lymphocytic Leukemia: A Case Report
Nwe Ni Than1*, Marcus Mottershead1, Gerald Langman2 and Alexander Daley11Department of Gastroenterology, Heart of England NHS Foundation Trust, Birmingham, United Kingdom
2Department of Histopathology, Heart of England NHS Foundation Trust, Birmingham, United Kingdom
- *Corresponding Author:
- Nwe Ni Than
Heart of England NHS Foundation Trust
B9 5SS, Birmingham, United Kingdom
Tel: 447738628170
E-mail: nwenithan@gmail.com
Received date: March 14, 2017; Accepted date: April 03, 2017; Published date: April 10, 2017
Citation: Than NN, Mottershead M, Langman G, Daley A (2017) Acute Upper Gastrointestinal Bleeding from Gastric Involvement of Chronic Lymphocytic Leukemia: A Case Report. J Gastrointest Dig Syst 7:499. doi: 10.4172/2161-069X.1000499
Copyright: © 2017 Than NN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Gastrointestinal involvement of chronic lymphocytic leukaemia (CLL) is uncommon and acute GI bleeding as a result of CLL involvement is much rarer. We report a 77-year-old lady with known history of chronic lymphocytic leukaemia (CLL) presented to emergency department with haematemesis and melaena. Upper gastrointestinal endoscopy showed large necrotic looking area in the stomach with bleeding from necrotic area. Biopsies showed lymphoid infiltration and immunohistochemistry showed CD20+, CD5+, Cyclin D1- and CD23- which were similar findings to CLL from bone marrow biopsy.
