Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Adiponectin and Resistin Levels in Umbilical Serum of Term Neonatesand Relation to Birth Weight

Saad Mohamed1, Ahmad El-Askary2* and Alaa Megahed3

1Department of Pediatrics, Al-Azhar University, Egypt

2Department of Medical Biochemistry, Al-Azhar University, Egypt & College of Applied Medical Sciences, Taif University, KSA

3Departments of Obstetrics and Gynecology, Al-Azhar University, Egypt

*Corresponding Author:
Ahmad El-Askary
Department of Medical Biochemistry
Al-Azhar University
Egypt & College of Applied Medical Sciences
Taif University, KSA
Tel: 00201010011697
E-mail: ahmadelaskary3@gmail.com

Received Date: April 29, 2017; Accepted Date: May 29, 2017; Published Date: June 2, 2017

Citation: Mohamed S, El-Askary A, Megahed A (2017) Adiponectin and Resistin Levels in Umbilical Serum of Term Neonates and Relation to Birth Weight. Neonat Pediatr Med 3: 127. doi:10.4172/2572-4983.1000127

Copyright: © 2017 Mohamed S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Optimal birth weight is an important factor for the future health of the newborns. Aberrations in fetal growth are associated with adverse health effects both in early life and in late childhood and adulthood. Fetal growth is controlled by both maternal hormones and nutrition. Adipokines, including resistin and adiponectin are known regulators of energy metabolism; although their role in the regulation of fetal growth still poorly understood. Objective: The aim of the present study was to evaluate the relationship between adiponectin and resistin with abnormalities of neonatal birth weight and to identify the correlation between these proteins and various maternal and neonatal factors. Patients and Methods: Comparative controlled study included 120 full term newborns recruited from Al-Azhar University Hospital (New Damietta), during the period from January 2016 to February 2017. Included newborns were divided into 3 groups; group 1) 40 small for gestational age (SGA) newborns, 2) 40 large for gestational age (LGA) newborns, and group 3) 40 apparently healthy appropriate for gestational age (AGA) newborns, were selected randomly. Serum umbilical cord adiponectin and resistin were measured by ELISA. Results: There was no significant difference between groups as regard to maternal age (P: 0.797), parity (P: 0.77), gestational age (P: 0.528) and BMI (P: 0.091). Umbilical cord resistin and adiponectin were significantly lower among LGA group (resistin: 16.9 ± 1.92 ng/ml; adiponectin: 6.74 ± 2.23 ᶙg/ml), and significantly elevated among SGA group (resistin: 23.03 ± 3.97 ng/ml; adiponectin: 14.92 ± 3.19 ᶙg/ml) than AGA group (resistin: 17.98 ± 1.89 ng/ml; adiponectin: 11.04 ± 1.91 ᶙg/ml; P

Keywords

Recommended Conferences
Google Scholar citation report
Citations : 303

Neonatal and Pediatric Medicine received 303 citations as per Google Scholar report

Indexed In
  • Google Scholar
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • ICMJE
Share This Page
Top