Journal of Alzheimers Disease & Parkinsonism
Open Access

Review Article

Alterations in Olfaction during Alzheimer Disease, Parkinson Disease and Lewy Body Disease

Patrick Manckoundia^1,2,*, Alain Putot¹, Rachid Mahmoudi^3,4, Mélanie Dipanda¹, Sophie Putot¹, Sanaa Asgassou¹, Anne-Julie Bianchi⁵ and Hélène Sordet-Guepet¹

¹Elderly Persons Pole, Hospital of Champmaillot, University Hospital, BP 87 909, 2 rue Jules Violle 21 079 Dijon Cedex, France

²INSERM U1093 Cognition Action Plasticite Sensorimotrice. Universite of Bourgogne Franche Comte BP 27877 F-21078 Dijon Cedex, France

³Department of Internal Medicine and Gerontology, University Hospital, Maison Blanche Hospital, Reims, F-51092, France

⁴University of Reims Champagne-Ardenne, Faculty of Medicine, E.A 3797, Reims, F-51092, France

⁵Department of Geriatric Rehabilitation, Hospital of Beaune, BP 40104, Avenue Guigone of Salins, 21203 Beaune Cedex, France

*Corresponding Author:

Patrick Manckoundia
Elderly Persons Pole, Hospital of Champmaillot University Hospital
BP87909, 2rueJules Violle 21 079 Dijon Cedex, France
Tel: 0380293970
E-mail: patrick.manckoundia@chu-dijon.fr

Received date October 10, 2016; Accepted date October 18, 2016; Published date October 25, 2016

Citation: Manckoundia P, Putot A, Mahmoudi R, Dipanda M, Putot S, et al. (2016) Alterations in Olfaction during Alzheimer Disease, Parkinson Disease and Lewy Body Disease. J Alzheimers Dis Parkinsonism 6: 274. doi: 10.4172/2161-0460.1000274

Copyright: © 2016 Manckoundia P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Increasing interest is being shown in the link between olfaction, a complex sensory system, and cognition, particularly in the elderly. Olfaction is known to affect cognitive abilities and mood. In this article, we consider the impairment of olfactory function due to Alzheimer disease (AD), Parkinson disease (PD) and Lewy body disease (LBD), through pathological changes in the peripheral and central olfactory structures. The high frequency of these olfactory disorders as well as their early occurrence in AD, PD and LBD suggest that they should be screened for in subjects suffering from these three neurodegenerative diseases.

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