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Case Report

Amniotic Band Syndrome: A Case Series

Srinivasan H1*, Dhungel P1, Harper T2 and Lampley C3
1Department of Pediatrics, Mount Sinai Hospital, Chicago, IL, USA
2Department of Pathology, Mount Sinai Hospital, Chicago, IL, USA
3Department of Obstetrics and Gynecology, Mount Sinai Hospital, Chicago, IL, USA
Corresponding Author : Dr Hari Srinivasan
Mount Sinai hospital. Pediatrics
15th and California, Chicago, IL 60608, USA
Tel : 7732575392
E-mail: hari.srinivasan@sinai.org
Received July 11, 2014; Accepted September 09, 2014; Published September 15, 2014
Citation: Srinivasan H, Dhungel P, Harper T, Lampley C (2014) Amniotic Band Syndrome: A Case Series. J Preg Child Health 1:109. doi: 10.4172/2376-127X.1000109
Copyright: © 2014 Srinivasan H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Three cases of amniotic band syndrome (ABS) were studied to highlight the clinicopathologic characteristics. The diagnosis was based on the following manifestations: cranio facial clefts; limb body wall defects and amniotic band attachment. All three cases were stillborn and associated with defects in the central nervous system, heart or gastrointestinal system. Phenotypic features included craniofacial clefting, thoracoabdominoschisis, amputation, ring constriction, amniotic band adhesion, placental adhesions, and internal malformations. When analyzing the phenotype in relation to their etiology, it was found that amniotic disruption, vascular disruption or genetic disruption could explain the amniotic band syndrome/limb body wall complexes, alone or in combinations.

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