Analytical Method Development and Validation: A Concise Review
- *Corresponding Author:
- Ashish Chauhan
SMPIC, NIPER, Mohali
E-mail: [email protected]
Received Date: January 28, 2015; Accepted Date: February 14, 2015; Published Date: February 23, 2015
Citation: Chauhan A, harti Mittu B, Chauhan P (2015) Analytical Method Development and Validation: A Concise Review. J Anal Bioanal Tech 6: 233. doi: 10.4172/2155-9872.1000233
Copyright: ©2015 Chauhan A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Analytical method development and validation are the continuous and inter-dependent task associated with the research and development, quality control and quality assurance departments. Analytical procedures play a critical role in equivalence and risk assessment, management. It helps in establishment of product-specific acceptance criteria and stability of results.Validation should demonstrate that the analytical procedure is suitable for its intented purpose. Design of experiment is a powerful tool for the method characterization and validation. Analytical professionals should be comfortable to use it to characterize and optimize the analytical method. An effective analytical method development and its validation can provide significant improvements in precision and a reduction in bias errors. It can further help to avoid costly and time consuming exercises.