Journal of Alzheimers Disease & Parkinsonism
Open Access

Can SARs-CoV-2 Infect Nasal Epithelium and Cause Parkinson's Disease?

Mohsen Rafie^1*, Farhad Azadmehr², Mostafa Taheri³, Aylar Mansouri4⁴ and Valentyna Mahdi Naeim⁵

¹Department of Clinical Psychology, University of Semnan, Semnan, Iran

²Department of Medical-Surgical Nursing, Urmia University of Medical Sciences, Urmia, Iran

³Department of Critical Care Nursing, Tehran University of Medical Sciences, Tehran, Iran

⁴Department of Psychology, Johannes Kepler University Linz, Linz, Austria

⁵Department of Critical Care Nursing, Islamic Azad University, Ardabil, Iran

Received Date: Jan 02, 2023 / Published Date: Jan 31, 2023

Citation: Rafie M, Azadmehr F, Taheri M, Mansouri A, Naeim VM (2023) Can SARs-CoV-2 Infect Nasal Epithelium and Cause Parkinson's Disease?. J Alzheimers Dis Parkinsonism 13:560.DOI: 10.4172/2161-0460.1000560

Warning: Undefined variable $i in /efsdata/omicsonline.org/httpdocs/peer-reviewed/abstract-page.php on line 156

Warning: Undefined variable $for_cr in /efsdata/omicsonline.org/httpdocs/peer-reviewed/abstract-page.php on line 156
Copyright: © 2023 Rafie M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

To read the full article Peer-reviewed Article PDF | Peer-reviewed Full Article

Background: The main trigger for Parkinson's disease is a mutated version of a protein called alpha-synuclein. This protein accumulates in dopamine-producing neurons. COVID-19 can increase the risk of Parkinson's and other neurological diseases.

Materials and Methods: This research study was conducted by the library method.

Results: The results showed that the virus can cause neuroinflammation, which, as a predisposing event, predisposes the brain to overreaction to subsequent neurological events. This secondary neurological event can be anything from another viral infection to poisoning and even aging. A secondary neurological event triggers an abnormal brain response that leads to nerve degeneration and eventually Parkinson's disease. The results show that the SARS-CoV-2 virus as a neurotropic virus can enter brain tissue.

Conclusion: Therefore, the virus certainly has the potential to act as a predisposing event in increasing the risk of Parkinson's disease.

Keywords