alexa Cholesterol Homeostasis and the Pathogenesis of Multiple System Atrophy
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Cholesterol Homeostasis and the Pathogenesis of Multiple System Atrophy

Chongfeng-Bi and Hairong-Qian*

Navy General Hospital of PLA, Beijing, China

*Corresponding Author:
Hairong-Qian
Department of Neurology
Navy General Hospital of PLA
Beijing 100048, China
Tel: +86 10 5625 9395
E-mail: [email protected]

Received date: April 12, 2017; Accepted date: May 26, 2017; Published date: June 02, 2017

Citation: Bi C, Qian H (2017) Cholesterol Homeostasis and the Pathogenesis of Multiple System Atrophy. J Alzheimers Dis Parkinsonism 7:330. doi:10.4172/2161-0460.1000330

Copyright: © 2017 Bi C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Multiple system atrophy (MSA) is a sporadic neurodegenerative disease among adults, which can be characterized by autonomic nerve dysfunction, Parkinsonism, ataxia and pyramidal tract dysfunction, or overlapped symptoms. It can mainly be divided into two types: Parkinsonism (MSA-P) and cerebellum type (MSA-C). The pathology of this disease is the accumulation of alpha-synuclein in oligodendrocyte. And because of this, it belongs to synucleinopathies. Alpha-synuclein is a kind of protein, which has a close connection with lipid membrane in the process of biosynthesis of central nervous system, and this close relationship may play a crucial role in the mechanism of alpha-synucleinopathies. Recently researchers who have focused on the serum lipids level in MSA patients are taking a stab at finding the diagnostic biomarkers, like serum cholesterol level, so as to develop effective therapies in the early stage of MSA. Therefore, the purpose of our review is to summarize the valuable part of recent researches on cholesterol level of MSA patients and to discuss the optimal way to evaluate MSA disease in a simple way to diagnose it early.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

busi[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords