Journal of Clinical Diabetes
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Mini Review   
  • J Clin Diabetes 2022, Vol 6(4): 145
  • DOI: 10.4172/jcds.1000145

Clozapine induces metformin-resistant prediabetes/diabetes that's related to poor clinical efficaciousness in patients with early treatment-resistant schizophrenic disorder

Halin Shao*
Department of Psychiatry, Albert Einstein College of Medicine, Morris Park Avenue, Bronx, U.S.A
*Corresponding Author : Halin Shao, Department of Psychiatry, Albert Einstein College of Medicine, Morris Park Avenue, Bronx, U.S.A, Email: halinshao.332@gmail.com

Received Date: Jun 29, 2022 / Published Date: Jul 29, 2022

Abstract

Two distinct subtypes of treatment-resistant dementia praecox (TRS) are recently rumored, as well as earlytreatment resistance (E-TR) and late-treatment resistance (L-TR). This study was to assess clozapine-induced metformin-resistant prediabetes/diabetes and its correlation with clinical effectiveness in dementia praecox E-TR subtype. The incidence of clozapine-induced metformin-resistant prediabetes/diabetes was significantly high in dementia praecox early-treatment resistance (E-TR) subtype. Clozapine-induced metformin-resistantprediabetes/diabetes depicted associate degree freelance risk issue that adversely affected the clinical effectiveness of neuroleptic agent for dementia praecox E-TR subtype. Switching to neuroleptic agent strategy ought to be reconsidered within the treatment of patients with dementia praecox E-TR subtype. Given the high incidence of metformin-resistant clozapine-induced prediabetes/diabetes, the viability of manner interventions to stop clozapineinduced prediabetes/diabetes in patients with dementia praecox E-TR subtype ought to be assessed in future studies.

Citation: Shao H (2022) Clozapine Induces Metformin-Resistant Prediabetes/ Diabetes that’s Related to Poor Clinical Efficaciousness in Patients with Early Treatment-Resistant Schizophrenic Disorder. J Clin Diabetes 6: 145. Doi: 10.4172/jcds.1000145

Copyright: © 2022 Shao H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Top