alexa Complete Histopathological Disappearance of Rectal Malt Lymphoma after Eradication of Helicobacter pylori Confirmed by ESD | OMICS International | Abstract
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
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Case Report

Complete Histopathological Disappearance of Rectal Malt Lymphoma after Eradication of Helicobacter pylori Confirmed by ESD

Jun Arimoto, Takuma Higurashi and Atsushi Nakajima*

Division of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan

*Corresponding Author:
Atushi Nakajima
Division of Gastroenterology and Hepatology
Yokohama City University School of Medicine
3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004 Japan
Tel: +81-45-7872640
Fax: +81-45-7843546
E-mail: [email protected]

Received date: February 24, 2015; Accepted date: March 1, 2015; Published date: March 18, 2015

Citation: Arimoto J, Higurashi T, Nakajima A (2015) Complete Histopathological Disappearance of Rectal Malt Lymphoma after Eradication of Helicobacter pylori Confirmed by ESD. J Gastrointest Dig Syst 5:263. doi:10.4172/2161-069X.1000263

Copyright: ©2015 Arimoto J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

In a 77-year-old Japanese housewife who was undergoing regular colonoscopy for follow-up of a colon polyp, a total colonoscopy showed an elevated lesion in the rectum. Histological findings of a conventional biopsy from the lesion showed a mucosa-associated lymphoid tissue (MALT) lymphoma, and the patient was diagnosed as having clinical stage 1 disease. We elected to administer antibiotic therapy as the serological test for anti-Helicobacter pylori antibody was positive and Helicobacter pylori was detected in a culture of the biopsy specimens. The antibiotic therapy was successful, however, colonoscopy after the eradication therapy showed a residual lesion. Histologic examination can’t deny the possibility of the presence of a residual MALT lymphoma. Endoscopic ultrasonography revealed that the lesion was confined to the mucosa. We performed endoscopic submucosal dissection (ESD) and histological examination of the ESD specimen showed complete disappearance of the tumor. The patient remains in complete remission now, 1 year after the treatment.

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