Considerations on Some Problems in Carcinoid Research
Professor Emeritus, Niigata University, Japan
- *Corresponding Author:
- Jun Soga
Niigata, 950-2074, Japan
Received date: Jun 10, 2013; Accepted date: September 30, 2013; Published date: October 03, 2013
Citation: Soga J (2013) Considerations on Some Problems in Carcinoid Research. J Gastroint Dig Syst 3:143. doi:10.4172/2161-069X.1000143
Copyright: © 2013 Soga J. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Three points of emphasis unrelated to each other are described. First: Detailed mechanism of the earliest carcinoid formation in the form of a budding phenomenon is clearly demonstrated in a colored photo of consective serial sections of the gastric gland. Second: The original drawing of the submucosal nodule for which the term “carcinoid” was proposed as a benign tumor is pointed out to be a result of malignant invasion of neoplastic cells originating in the mucosa and penetrating the muscularis mucosae. Third: Based on the concept that the term “carcinoid” is a misnomer, an alternative term “endocrinocarcinoma (ECC)” is roposed.