Constructional Apraxia is related to Different Cognitive Defect s across DementiaNatascia De Lucia1*, Silvio Peluso1, Anna De Rosa1, Elena Salvatore1, Giuseppe De Michele1 and Dario Grossi2
- *Corresponding Author:
- Natascia De Lucia
Department of Neurosciences, Reproductive and Odontostomatological Sciences
“Federico II” University, Naples, Italy
Tel: +39 0817463711
E-mail: [email protected]
Received date: June 09, 2016; Accepted date: June 23, 2016; Published date: June 30, 2016
Citation: De Lucia N, Peluso S, De Rosa A, Salvatore E, De Michele G, et al. (2016) Constructional Apraxia is related to Different Cognitive Defects across Dementia. J Alzheimers Dis Parkinsonism 6:244. doi:10.4172/2161-0460.1000244
Copyright: © 2016 De Lucia N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: In visuo-constructional copying tasks, individuals with dementia can reproduce distorted or simplified figures resulting in the so-called ‘Constructional apraxia’ (CA) impairment. CA has been often described in Alzheimer’s disease (AD), Vascular dementia (VAD), or Fronto-temporal dementia (FTD), and less often in patients with Parkinson’s disease and associated dementia (PDD). There have been suggestions that different cognitive mechanisms could account for CA in different forms of dementia, but this hypothesis has not been directly verified. In the present study we explored visuo-constructional abilities in a sample of AD, VAD, FTD and PDD patients. We also investigated the cognitive factors associated to CA in these patients’ groups. Methods: We enrolled 72 AD patients, 61 VAD patients, 33 FTD patients and 32 PDD patients. All the patients underwent a copying drawings task to assess CA, and an extensive neuropsychological assessment of frontal/ executive, visuo-spatial, and memory skills. Results: FTD patients showed significant higher scores on drawing copying task compared to all other groups, whereas similar scores were observed between AD, VAD and PDD patients. Moreover, CA was strongly related to visuo-spatial impairments in AD and PDD patients and to frontal/executive impairments in VAD and FTD patients. Conclusion: Our findings suggest that CA could be ascribed to distinctive cognitive defects in the different forms of dementia.