ISSN: 2153-0777

Journal of Bioengineering and Bioelectronics
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Current Applications of Tissue Engineering in Biomedicine

Cristina Castells-Sala, Mireia Alemany-Ribes, Teresa Fernández-Muiños, Lourdes Recha-Sancho, Patricia López-Chicón, Caterina Aloy- Reverté, Javier Caballero-Camino, Alejandro Márquez-Gil and Carlos E Semino*
IQS School of Engineering, Ramon Llull University, Via Augusta 390, 08017 Barcelona, Spain
Corresponding Author : Carlos E Semino
IQS School of Engineering, Ramon Llull University
Via Augusta 390, 08017 Barcelona, Spain
E-mail: carlos.semino@iqs.url.edu
Received May 06, 2013; Accepted August 20, 2013; Published August 22, 2013
Citation: Castells-Sala C, Alemany-Ribes M, Fernandez-Muiños T, Recha-Sancho L, Lopez-Chicon P et al. (2013) Current Applications of Tissue Engineering in Biomedicine. J Biochip Tissue chip S2:004. doi:10.4172/2153-0777.S2-004
Copyright: © 2013 Castells-Sala C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Tissue Engineering (TE) is a scientific field mainly focused on the development of tissue and organ substitutes by controlling biological, biophysical and/or biomechanical parameters in the laboratory. The result corresponds, in most cases, to the elaboration of three-dimensional cellular constructs with properties more similar to natural tissues than classical monolayer cultures. These systems enable the in vitro study of human physiology and physiopathology more accurately, while providing a set of biomedical tools with potential applicability in toxicology, medical devices, tissue replacement, repair and regeneration. To succeed in these purposes, TE uses nature as an inspiration source for the generation of extracellular matrix analogues (scaffolds), either from natural or synthetic origin as well as bioreactors and bio-devices to mimic natural physiological conditions of particular tissues. These scaffolds embed cells in a threedimensional milieu that display signals critical for the determination of cellular fate, in terms of proliferation, differentiation and migration, among others. The aim of this review is to analyze the state of the art of TE and some of its application fields: bone, cartilage, heart, pancreas, vascular and cancer.

Keywords

Top