Decoding Host-Pathogen Networks for Novel Therapies
Abstract
This body of research explores the intricate molecular dynamics governing host-pathogen interactions, revealing diverse strategies employed by microbes for survival and pathogenesis. Key areas include metabolic hijacking, immune evasion by bacteria and fungi, and viral protein manipulation. Studies also examine the role of microbiota, epigenetic reprogramming, and bacteriophage influence. Innovative approaches focus on metabolic vulnerabilities and systems biology to identify new antimicrobial targets. Collectively, these insights advance our understanding of infection mechanisms, paving the way for novel therapeutic interventions against a range of pathogens and combating antimicrobial resistance.
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