alexa Detection of Soluble Oligomers Formed by PB1-F2 Influenza A Virus Protein <em>in vitro</em> | OMICS International | Abstract
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
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Short Communication

Detection of Soluble Oligomers Formed by PB1-F2 Influenza A Virus Protein in vitro

Jasmina Vidic *, Ronan Le Goffic, Anna Miodek, Christiane Bourdieu, Charles-Adrien Richard, Mohammed Moudjou, Bernard Delmas, and Christophe Chevalier*

Virologie et Immunologie Moléculaires, Institut National de la Recherche Agronomique, 78350 Jouy en Josas, France

*Corresponding Author:
Jasmina Vidic
Virologie et Immunologie Moléculaires
Institut National de la Recherche Agronomique
78350 Jouy en Josas, France
Tel: +0033134652623
Fax: +0033134652621
E-mail: [email protected]
 
Christophe Chevalier
Virologie et Immunologie Moléculaires
Institut National de la Recherche Agronomique
78350 Jouy en Josas, France
Tel: +0033134652623
Fax: +0033134652621
E-mail: [email protected]

Received date: June 05, 2013; Accepted date: July 20, 2013; Published date: July 23, 2013

Citation: Vidic J, Le Goffic R, Miodek A, Bourdieu C, Richard CA, et al. (2013) Detection of Soluble Oligomers Formed by PB1-F2 Influenza A Virus Protein in vitro. J Anal Bioanal Tech 4:169. doi: 10.4172/2155-9872.1000169

Copyright: © 2013 Vidic J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Influenza A viruses (IAV) remain a major cause of respiratory disease worldwide each year and have been responsible for three main pandemics during the last century comprising the Spanish flu which killed up to 50 million of people. IAV are RNA enveloped viruses belonging to the Orthomyxoviridae family. The nature of the genome of IAV favors the constant and hardly predictable emergence of new strains such as highly virulent H5N1 viruses since 2003, or the H1N1 2009 pandemic strain. Recently, new human cases of severe respiratory illness with a new avian influenza A (H7N9) virus have been reported in China (mortality rate of 60%).Thus, researchers maintain their efforts to determine specific markers of virulence and to evaluate the potential of emerging strains to cause new pandemics.

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