Endoscopic Therapy for Early Esophageal NeoplasiaHendrik Manner*
Department of Internal Medicine II, HSK Wiesbaden, Germany
- *Corresponding Author:
- Hendrik Manner
Head of Endoscopy
Department of Internal Medicine II
HSK Wiesbaden, Germany
E-mail: [email protected]
Received date: July 18, 2014; Accepted date: September 12, 2014; Published date: September 19, 2014
Citation: Manner H (2014) Endoscopic Therapy for Early Esophageal Neoplasia. J Gastroint Dig Syst 4:218. doi:10.4172/2161-069X.1000218
Copyright: © Manner H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Endoscopic treatment of early esophageal neoplasia has widely been established in gastroenterology. It has
been shown to be effective and safe also in the long-term follow-up, and it is – in contrast to the previous goldstandard,
which is esophageal resection – organ preserving. There is no treatment-related mortality and a very low
In early Barrett’s neoplasia, the two-step concept of endoscopic resection (ER) of all neoplasia and thermal
ablation of the non-neoplastic remainder of the Barrett’s segment is the treatment of choice, combining a high rate of
curation with a low risk of treatment-related stricture formation.
There are two ER techniques for early esophageal neoplasia: The suck-and-cut technique and endoscopic
submucosal dissection, the latter one mainly used for squamous cell cancer. For thermal ablation, radiofrequency
ablation (RFA) and argon-plasma coagulation (APC) are mainly used.