alexa Eosinophilic Esophagitis- Clinical Management in Adults
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Eosinophilic Esophagitis- Clinical Management in Adults

Kouklakis S Georgios*, Vradelis D Stergios and Dellaportra Erminia

Professor of Gastroenterology Democritus University of Thrace, Greece

*Corresponding Author:
Kouklakis S. Georgios
Professor of Gastroenterology Democritus University of Thrace, Greece
Tel: 00302551351003
E-mail: [email protected]

Received date: September 03, 2014; Accepted date: September 30, 2014; Published date: October 06, 2014

Citation: Georgios KS, Stergios VD, Erminia D (2014) Eosinophilic Esophagitis- Clinical Management in Adults. J Gastroint Dig Syst 4:226. doi:10.4172/2161-069X.1000226

Copyright: © 2014 Georgios KS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Eosinophilic esophagitis (EoE) represents a chronic, immune-mediated esophageal disease, characterized
clinically by symptoms related to esophageal dysfunction, histologically by eosinophilic infiltration of esophageal
mucosa and endoscopically by a range of abnormalities. EoE is increasing in prevalence and predominantly affects
children and young males, with a racial predilection of the patients being Caucasian. The relationship between EoE
and gastroesophageal reflux disease (GERD) can be complex, since their clinical and pathologic features may
overlap. Furthermore, an entity that can be considered a subtype of GERD or EoE is the proton pump inhibitorresponsive
esophageal eosinophilia (PPI-REE). PPI-REE emerged from the observation that some patients who
appeared to have EoE would have a clinical and histologic response to PPI treatment. Currently, upper endoscopy
with esophageal biopsies is the only way to diagnose EoE. Fifteen eosinophils//high-power field (hpf) are considered
a minimum threshold for the diagnosis of EoE, since the disease is isolated to the esophagus and other causes of
esophageal eosinophilia are excluded. Patients commonly have concurrent allergic diatheses, especially to food.
The therapeutic options of EoE include: chronic elimination diet, topical corticosteroids and esophageal dilation. We
review the latest approach to clinical diagnosis and management of EoE.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version