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Esophageal and Gastric Cancers in Sub-Saharan Africa, Epidemiological and Clinical Review | OMICS International | Abstract
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

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Review Article

Esophageal and Gastric Cancers in Sub-Saharan Africa, Epidemiological and Clinical Review

Dia Daouda1*, Mbengue Mouhamadou1, Bassene Marie Louise2 and Diouf Mamadou Lamine2
1Service de gastroenterologie Hospital General de Grand Yoff, BP 3270, Dakar, Senegal
2Service de gastroenterologie Hospital Aristide Le Dantec, BP 3001, Dakar, Senegal
Corresponding Author : Dia Daouda
Service General Hospital Gastroenterology Grand Yoff
BP 3270, Dakar, Senegal
E-mail: [email protected]
Received March 25, 2013; Accepted April 27, 2013; Published April 29, 2013
Citation: Daouda D, Mouhamadou M, Louise BM, Lamine DM (2013) Esophageal and Gastric Cancers in Sub-Saharan Africa, Epidemiological and Clinical Review. J Gastroint Dig Syst S6:007. doi:10.4172/2161-069X.S6-007
Copyright: © 2013 Daouda D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


The data on esophageal and gastric cancers in sub-Saharan Africa are fragmented and not numerous because of the rarity and of the inaccessibility of the diagnostic means. Esophageal cancer has very variable incidences according to the geographical zones there and nutritional and infectious factors are incriminated in its arisen. It reaches young subjects with a preferential siege the average esophagus with ascendancy of squamous cell carcinomas. For gastric cancer, its incidence there is low despite the strong prevalence of Helicobacter pylori infection. As in Western countries, Helicobacter pylori’s gene Cag A is correlated in its arisen there but the low prevalence of strains with multiple EPIYA-C segments might contribute to its low incidence. It affects young subjects more often male with a big ascendancy of adenocarcinoma. The improvement of the diagnostic conditions and the financing of researches are necessary for a better knowledge of the risk and the protective factors of esophageal and gastric cancers in sub-Saharan Africa.