Research Article
Ethnic Differences in Inflammatory Bowel Diseases
Souad Bouhadan* and Tom G Moreels
Antwerp University Hospital, Department of Gastroenterology & Hepatology, Wilrijkstraat 10, 2650 Edegem-Antwerp, Belgium
- *Corresponding Author:
- Souad Bouhadan
Department of Gastroenterology & Hepatology
Antwerp University Hospital, Wilrijkstraat 10
2650 Edegem-Antwerp, Belgium
Tel: +3238213324
Fax: +3238214478
E-mail: souad.bouhadan@uza.be
Received date: January 23, 2014; Accepted date: February 20, 2014; Published date: February 25, 2014
Citation: Bouhadan S, Moreels TG (2014) Ethnic Differences in Inflammatory Bowel Diseases. J Gastroint Dig Syst 4:173. doi:10.4172/2161-069X.1000173
Copyright: © 2014 Bouhadan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
have investigated all first and second degree immigrants from our IBD patient cohort. In Antwerp – Belgium there is an important Moroccan immigrant population since the 1960s. Phenotype differences were assessed between Moroccan and Caucasian immigrants. We looked at age at diagnosis, sex, disease location and behavior (Montreal classification), extraintestinal manifestations, need for anti-TNFα treatment and surgery. Our single-center results suggest that first and second degree Moroccan immigrants with IBD suffer predominantly from Crohn’s disease with a more severe phenotype characterized by penetrating disease leading to higher rates of CD-related surgery and need for anti-TNFα treatment. In addition, extraintestinal manifestations tend to be more prevalent in the Moroccan immigrant population. Possible explanations are discussed.