Evolution and Outcome of Eight Patients Undergoing Treatment of Gastroesophageal Disease by EsophyxAntoine Abi Abboud* and Walid Abdel Khalek
Medicine Division of Gastroenterology, Faculty of Medical Sciences, Lebanese University, Lebanon
- Corresponding Author:
- Antoine Abi Abboud
Medicine Division of Gastroenterology
Faculty of Medical Sciences
Lebanese University, Lebanon
E-mail: [email protected]
Received Date: April 22, 2017; Accepted Date: May 09, 2017; Published Date: May 16, 2017
Citation: Abboud AA, Khalek WA (2017) Evolution and Outcome of Eight Patients Undergoing Treatment of Gastroesophageal Disease by Esophyx. J Gastrointest Dig Syst 7:504. doi:10.4172/2161-069X.1000504
Copyright: © 2017 Abboud AA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Gastroesophageal reflux disease (GERD) is arguably the most common disease encountered by the gastroenterologist. It is mainly caused by defects in the lower esophageal sphincter (LES) that induces spontaneous transient LES relaxations (tLESRs). This is a chronic condition with typical and atypical, sometimes troublesome manifestations requiring long term treatment. Anti-reflux surgery is an alternative option. The TIF (transoral incisionless fundoplication) procedure by offering some advantages over surgery could be recommended for patients whose symptoms recur upon discontinuation of the medications. This study intended to assess the safety and efficacy of TIF for treating GERD.
Methods: A prospective trial was conducted at Lebanese Hospital Geitaoui University Medical Center and Middle East Institute of Health in Lebanon, on 8 patients, age 28-55 years, with chronic GERD, symptoms (>5 years), undergoing EsophyX procedure and followed for 1 year after their procedure. Information concerning the patients was gathered using an international questionnaire (GERD-HRQL, Health Related Quality of Life questionnaire) filled by the treating physician.
Results: When compared to scores before TIF and without medications, the GERD-HRQL scores were significantly reduced one year after the procedure. Regurgitation experienced was reduced to 62.5% compared to 75% while patients were off PPI. Symptoms free (GERD-HRQL score ≤ 12) achieving complete cessation of medications, were reported by 25% of patients. Overall 37.5% of patients were satisfied, 12.5% neutral, and 50% less satisfied with their results.