alexa Gastric Synchronous Stromal Tumor and Adenocarcinoma: A Fortuitous Association?
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
Open Access

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Case Report

Gastric Synchronous Stromal Tumor and Adenocarcinoma: A Fortuitous Association?

Haddad Anis*, Kacem Selma, Sebai Amine, Maghrebi Houcine, Makni Amine and Kacem Montassar

Department of Surgery “A”, La Rabta Hospital, Tunis, Tunisia

*Corresponding Author:
Haddad Anis
Department of Surgery “A”, La Rabta Hospital, Tunis, Tunisia
Tel: +21650928386
E-mail: [email protected]

Received date: March 23, 2017; Accepted date: August 04, 2017; Published date: August 09, 2017

Citation: Anis H, Selma K, Amine S, Houcine M, Amine M, et al. (2017) Gastric Synchronous Stromal Tumor and Adenocarcinoma: A Fortuitous Association?. J Clin Exp Pathol 7:320. doi: 10.4172/2161-0681.1000320

Copyright: © 2017 Anis H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The association of an adenocarcinoma with a stromal tumor in the stomach is rarely observed. We report the observation of a patient operated for a synchronous tumor associating subcardial adenocarcinoma with a stromal tumor of the gastric body. It is a 74 year-old patient, diabetic, who was admitted, in December 2016, for epigastralgia associated with vomiting evolving for 2 months. Physical examination was strictly normal. An oesogastroduodenal fibroscopy was performed showing a subcardial ulcerative budding formation with a 3 cm diameter and the presence, in the gastric body, of a second sub mucosal nodular formation with a 4 cm diameter. The anatomopathological examination of the biopsies concluded to an infiltrating and slightly differentiated adenocarcinoma at the subcardial level associated with chronic HP+ gastritis without signs of malignancy. The computed tomography, performed as part of the extension study, revealed a macro-lobulated tissue mass, posterior, pre-pyloric, with submucosal development, prolapsed in the peritoneum whose enhancement characteristics evoke a stromal tumor but also an irregular gastric cardio-tuberosal thickening predominant on the small gastric curvature and associated with necrotic pre-gastric centimetric satellite ganglia. The patient had a total gastrectomy with lymph node dissection type D1, 5 and oesojejunal anastomosis on a Y-shaped loop. The anatomo-pathological examination of the surgical specimen concluded to a slightly differentiated adenocarcinoma of the cardia classified as pT3N2 associated with a stromal tumor of the gastric body Synchronous development of gastric adenocarcinoma and GIST is rare. During this association, the stromal tumor is often characterized by low risk of recidivism.

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