alexa Hemosiderosis due to Chronic Alcoholism | OMICS International
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Hemosiderosis due to Chronic Alcoholism

Pinar Tosun Tasar1*, Ozlem Ozdemir1, Omer Binicier2 and Omer Selahattin Topalak2

1 Department of Internal Medicine, Dokuz Eylul University Faculty of Medicine, Izmir/Turkey

2 Department of Internal Medicine, Division of Gastroenterology, DokuzEylul University Faculty of Medicine, Izmir/Turkey

*Corresponding Author:
Pinar TosunTasar
Department of Internal Medicine
DokuzEylül University Faculty of Medicine, Izmir, Turkey
Tel: +9005053988985
E-mail: [email protected]

Received date: March 11, 2014; Accepted date: March 28, 2014; Published date: April 01, 2014

Citation: Tasar PT, Ozdemir O, Binicier O, Topalak OS (2014) Hemosiderosis due to Chronic Alcoholism. J Gastroint Dig Syst 4:182. doi:10.4172/2161-069X.1000182

Copyright: © 2014 Tasar PT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Alcoholic liver disease is characterized with excess consumption of alcohol for long term and variable hepatic injury. Chronic alcohol consumption often leads to a disease called alcoholic liver disease [ALD]. It is generally with an accompaning iron accumulation. Increased plasma iron levels and tissue iron overload stimulate synthesis of hepcidin, resulting with release of iron from macrophages and duodenal enterocytes to the plasma. This homeostasis ensures that plasma iron level is maintained within a constant range and excess absorption and accumulation of iron in tissues are prevented. Alcohol-induced oxidative stress in hepatocytes is one of the main mechanisms by which hepcidin expression in the liver is down-regulated by alcohol. The decrease in liver hepcidin synthesis leads to an increase in intestinal iron transport and liver iron content. We report a case hemosiderosis secondary to chronic alcoholism.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version