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High Concentration of Tumor Marker Cancer Antigen CA15-3 in Breast CancerPatients after Surgery | OMICS International| Abstract
ISSN: 2572-4118

Breast Cancer: Current Research
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  • Research Article   
  • Breast Can Curr Res, Vol 1(4)Vol 1(4): 114
  • DOI: 10.4172/2572-4118.1000114

High Concentration of Tumor Marker Cancer Antigen CA15-3 in Breast CancerPatients after Surgery

Adam MA Osman1*, Mohamed E Hamid2, Ayda H Satti3 and Ibtisam A Goreish4
1Department of Animal Resource, Ministry of Agriculture, , Kingdom of Saudi Arabia, Abha, Saudi Arabia
2Department of Clinical Microbiology and Parasitology, College of Medicine, King Khalid University, Box 641, Abha 61314, Saudi Arabia
3Department of Surgery, Khartoum Teaching Hospital, , Khartoum, Sudan
4Director General of Animal Resources Research Corporation, , Khartoum, Sudan
*Corresponding Author : Adam MA Osman, Department of Animal Resource, Ministry of Agriculture, Kingdom Of Saudi Arabia, Abha, Saudi Arabia, Tel: 00966550979809, Email: mohammedai41@yahoo.com

Received Date: Oct 20, 2016 / Accepted Date: Nov 08, 2016 / Published Date: Nov 14, 2016

Abstract

Background: Cancer antigen15-3 (CA15-3) is the most common tumor marker in breast cancer patients. The aim of the study analysis was to investigate the correlation, if there is any, of the levels of CA15-3 in patients with breast cancer and healthy females and to evaluate the efficacy of cancer associated antigen 15-3 (CA15-3) in monitoring breast cancer.
Methods: Clinical assessment was carried out in 40 serum samples. Female patient (n=20) were histologically verified of having breast cancer after chemical treatment and surgery. Healthy females subjects (n=20) with no history of breast cancer were included as controls. Enzyme linked immunosorbent assays was used for the quantitative determination of the cancer associate antigen.
Result: Elevation of CA15-3 levels was found associated with breast cancer patients. The serological levels were found around 75.04 ± SD/ mL (P=0.001), whereas the level among the control group was 13.99 ± SD/ mL).
Conclusion: CA15-3 concentration levels were found elevated in breast cancer patients with significant level demonstrating its diagnostic routine use.

Keywords: Breast cancer; Metastasis; Tumor; Chemotheray; Blood sample

Citation: Osman MAA, Hamid ME, Satti AH, Goreish IA (2016) High Concentration of Tumor Marker Cancer Antigen CA15-3 in Breast Cancer Patients after Surgery. Breast Can Curr Res 1: 114 Doi: 10.4172/2572-4118.1000114

Copyright: © 2016 Osman MAA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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