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Intraosseous Meningioma Masquerading as Fibrous Dysplasia | OMICS International| Abstract
ISSN: 2476-2024

Diagnostic Pathology: Open Access
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  • Research Article   
  • Diagn Pathol Open 2016, Vol 1(1): 104
  • DOI: 10.4172/2476-2024.1000104

Intraosseous Meningioma Masquerading as Fibrous Dysplasia

Solomon S Shaftel1, Ramzi M Alameddine1, Sang-Rog Oh1, Bobby S Korn1,2, Jonathan H Lin3 and Don O Kikkawa1,2*
1Division of Oculofacial Plastic and Reconstructive Surgery, UCSD Department of Ophthalmology, Shiley Eye Institute, , La Jolla, California, USA
2UCSD Division of Plastic Surgery, , La Jolla, California, USA
3UCSD Department of Pathology, , La Jolla, California, USA
*Corresponding Author : Don O Kikkawa, Professor of Clinical Ophthalmology, Division of Oculofacial Plastic and Reconstructive Surgery, UCSD Department of Ophthalmology, Shiley Eye Institute, La Jolla, California, USA, Tel: +1 (305) 713-3802, Fax: +961 03-404751, Email: [email protected]

Received Date: Oct 02, 2015 / Accepted Date: Jan 04, 2016 / Published Date: Jan 08, 2016


Background: Intraosseous meningiomas often display clinical and radiologic features that can be confused for fibrous dysplasia. Histopathology usually confirms the diagnosis. We present a case initially misdiagnosed as fibrous dysplasia by histopathology.
Methods: A 58-year-old male presented with worsening proptosis and vision loss. He was previously diagnosed with fibrous dysplasia at an outside institution, with histologic confirmation of the diagnosis during orbital decompression.
Results: On examination there was evidence of optic neuropathy and mild restriction of gaze. Imaging revealed a large ossified mass of the greater sphenoid wing. Craniotomy and surgical decompression resulted in improved vision and symptoms. Histopathology revealed meningioma with bony and dural components.
Conclusions: This case emphasizes the need for a high level of suspicion and representative biopsies to reach prompt diagnosis of meningiomas in cases of recurrent or atypical fibrous dysplasia

Keywords: Intraosseous meningiomas; Benign fibrous dysplasia; CT imaging

Citation: Shaftel SS, Alameddine RM, Oh SR, Korn BS, Lin JH, et al. (201) Intraosseous Meningioma Masquerading as Fibrous Dysplasia. Diagn Pathol open 1: 104. Doi: 10.4172/2476-2024.1000104

Copyright: ©2015 Shaftel SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Review summary

  1. Harman Dhillon
    Posted on Aug 24 2016 at 2:19 pm
    The authors reported the occurrence of primary extradural intraosseous meningioma in a 58 year old male. The authors presented the histopathological results of the patient and discussed the whole process of diagnosis, prognosis as well as treatment of the disease. The article provides novel information on the disease and will act as a guiding reference for young doctors.