alexa Introducing the Effect of Chinese Chlorella as a Photosensitizing Drug at Different Temperatures | OMICS International| Abstract

ISSN: 2329-9053

Journal of Molecular Pharmaceutics & Organic Process Research

  • Editorial   
  • J Mol Pharm Org Process Res 2013, Vol 1(3): e109
  • DOI: 10.4172/2329-9053.1000e109

Introducing the Effect of Chinese Chlorella as a Photosensitizing Drug at Different Temperatures

M-Ali H Al-Akhras1*, Aljarrah K1, Ghaseb N Makhadmeh2 and Al Shorman3
1Department of Physics, Bio-Medical Physics Laboratory, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan
2Department of Nano Biotechnology Physics, USM University, Malaysia
3Institute of Science Mol’eculaires Orsay (ISMO), , CNRS UMR 8214, university’s Paris-Sud, Batiment 350, F-91405 Orsaycedex, France
*Corresponding Author : M-Ali H Al-Akhras, Department of Physics, Bio-Medical Physics Laboratory, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan, Tel: +962-2-7201000, Fax: +962-2-7201071, Email: [email protected]

Received Date: Jul 22, 2013 / Accepted Date: Jul 26, 2013 / Published Date: Aug 02, 2013

Abstract

Chinese Chlorella is natural algae seafood is widely used as a food substitute. Treatment of localized cancer cells by natural photosensitizer drugs extracted from herbs received intensive improvements with very high demands. Fractional hemolysis of the red blood cells incorporated with Chinese Chlorella in vitro has been reported. Continuous and delayed photohemolysis at different concentrations and different irradiation times were investigated. The samples irradiated with high-pressure arc lamp of intensities 58.07 J/cm2 ± 1.45 and 64.21 J/cm2 ± 1.98. The power dependent parameters of the relationship between time required to rupture 50% of the cells (t50) with different concentration and different irradiation time are found to be 0.63 ± 0.06 and 3.38 ± 0.17 respectively. These results suggested that, Chinese Chlorella could be one of the natural potential drugs in photodynamic therapy.

Keywords: Chinese chlorella; Photohemolysis; Photodynamic therapy; Power dependent

Citation: Al-Akhras MAH, Aljarrah K, Makhadmeh GN, Shorman A (2013) Introducing the Effect of Chinese Chlorella as a Photosensitizing Drug at Different Temperatures. J Mol Pharm Org Process Res 1: e109 Doi: 10.4172/2329-9053.1000e109

Copyright: ©2013 Al-Akhras MAH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

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