alexa In-vitro Antimicrobial Activity of Essential Oils and Different Organic Extracts of <em>Lippia alba</em> | OMICS International| Abstract

Journal of Phytochemistry & Biochemistry
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Research Article   
  • J Phytochemistry Biochem,

In-vitro Antimicrobial Activity of Essential Oils and Different Organic Extracts of Lippia alba

Islam MJ1, Amin MR1, Ahmed MF1, Khatun S1, Rahman ML1, Siddiqui SA2, Rahman MA2*, Kudrat-E-Zahan M3 and Mannan MA3*
1Bangladesh Council of Scientific and Industrial Research, , Rajshahi, Bangladesh
2Department of Applied Chemistry and Chemical Engineering, Islamic University, Bangladesh
3Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh
*Corresponding Author (s) : Md. Rahman MA, Department of Applied Chemistry and Chemical Engineering, Islamic University, Bangladesh, Tel: 8807174900, Email: [email protected]
Md. Mannan MA, Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh, Tel: 8801753841119, 880721 751512, Email: [email protected]

Received Date: Feb 15, 2018 / Accepted Date: Feb 21, 2018 / Published Date: Feb 28, 2018


The aim of this study was to investigate antibacterial activity of essential oils and different organic extractives extracted from the medicinal plant Lippia alba. The chemical composition of the hydrodistilled oil was determined by GC-MS spectroscopy. Typical eighty eight components representing 96.14% of the total oil was identified of which spathulenol (3.03%), caryophyllene oxide (6.39%), aromadendrene oxide-(2) (2.82%), alloaromadendrene oxide-(1) (2.46%), ledene oxide-(ii) (2.8%), α-caryophyllene, (1R)-(-)-myrtenal, 1-octen-3-ol (2.77 at.%), 1H-cyclopenta[1,3] cycloprop[1,2]benzene and myrtenyl acetates (3.29%) were the major components. The antibacterial activity was determined in vitro using agar diffusion method and the MIC determination test against six pathogenic bacteria. The essential oils and different extracts (5.0 μL disc–1 correspond to 500 and 250 μg disc–1) displayed a great potential of antibacterial activity against Gram-positive (Sarcina lutea, Bacillus subtilis) and Gram-negative bacteria (Xanthomonas campestries, Escherichia coli, Pseudomonas sp. and Klebsiella preumoniae). The zones of inhibition of different concentrations of the essential oils and the extracts against the tested bacteria were found in the range of 6~23 mm and the minimum inhibitory concentrations (MIC) were recorded between 1.95~500 μg disc–1. The results obtained from this study demonstrated that the natural product derived from Lippia alba might be used in pharmaceutical, cosmetic and agro-industries as natural preservatives or flavoring to control pathogenic microbes.

Keywords: Lippia alba; Essential oils; Organic extracts; Antibacterial activity; GC-MS spectroscopy

Citation: Islam MJ, Amin MR, Ahmed MF, Khatun S, Rahman ML, et al. (2018) Invitro Antimicrobial Activity of Essential Oils and Different Organic Extracts of Lippia alba. J Phytochemistry Biochem 2: 107.

Copyright: © 2018 Islam MJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Article Usage
  • Total views: 2064
  • [From(publication date): 0-2018 - Aug 11, 2020]
  • Breakdown by view type
  • HTML page views: 1905
  • PDF downloads: 159