Liposomes for Drug Delivery | OMICS International| Abstract
ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
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  • Review Article   
  • J Biotechnol Biomater,
  • DOI: 10.4172/2155-952X.1000276

Liposomes for Drug Delivery

Durgavati Yadav1, Kumar Sandeep2, Deepak Pandey3 and Ranu Kumari Dutta4*
1Department of Medicinal Chemistry, , IMS, BHU, Varanasi, India
2Department of Preventive Oncology, , BRAIRCH, AIIMS, New Delhi, India
3Department of Reproductive Biology, , AIIMS, New Delhi, India
4Department of Physics, University of Allahabad, Allahabad, UP, India
*Corresponding Author : Ranu Kumari Dutta, Department of Physics, University of Allahabad, Allahabad, UP, India, Tel: +919789111454, Email: [email protected]

Received Date: Sep 25, 2017 / Accepted Date: Oct 30, 2017 / Published Date: Nov 06, 2017


Liposomes are a novel drug delivery system (NDDS), they are vesicular structures consisting of bilalyers which form spontaneously when phospholipids are dispersed in water. They are microscopic vesicles in which an aqueous volume is entirely enclosed by a membrane composed of lipid bilayers. NDDS aims to deliver the drug at a rate directed by the needs of the body during the period of treatment and direct the place of action. Liposomes are colloidal spheres of cholesterol non-toxic surfactants, sphingolipids, glycolipids, long chain fatty acids and even membrane proteins and drug molecules or it is also called vesicular system. It differs in size, composition and charge and drug carrier loaded with variety of molecules such as small drug molecules, proteins, nucleotides or plasmids etc. Few drugs are formulated as liposomes to improve their therapeutic index. Hence a number of vesicular drug delivery systems such as liposomes, niosomes, transfersomes and pharmacosomes are developed. The focus of this chapter is to the various method of preparation, characterization of liposomes, advantages and applications, etc.

Keywords: Liposomes; Characterization; Drug delivery; Medicine; Stability

Citation: Yadav D, Sandeep K, Pandey D, Dutta RK (2017) Liposomes for Drug Delivery. J Biotechnol Biomater 7: 276. Doi: 10.4172/2155-952X.1000276

Copyright: 2017 Yadav D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited