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Measuring Quality of Life in Intellectually Disabled Persons with Dementia with the Italian Version of the Quality of Life in Late-Stage Dementia (QUALID) Scale | Abstract
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
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Research Article

Measuring Quality of Life in Intellectually Disabled Persons with Dementia with the Italian Version of the Quality of Life in Late-Stage Dementia (QUALID) Scale

De Vreese LP1, Uberti M2, Mantesso U4, De Bastiani E4, Weger E4, Marangoni AC4, Weiner MF3 and Gomiero T4*

1Department of Primary Care, Psychogeriatric Service, Local Health District, Modena, Italy

2Sospiro Foundation, Cremona, Italy

3Department of Psychiatry, University of Texas, Southwestern Medical Center, Dallas, USA

4ANFFAS Onlus Trentino, Italy

Corresponding Author:
Tiziano Gomiero
ANFFAS Trentino Onlus, Via G.B. Trener, 8
38121, Trento, Italy
Tel: +39-0461-407511
Fax: +39- 0461-407500

Received date: October 07, 2011; Accepted date: December 26, 2011; Published date: December 26, 2011

Citation: De Vreese LP, Uberti M, Mantesso U, De Bastiani E, Weger E, et al. (2012) Measuring Quality of Life in Intellectually Disabled Persons with Dementia with the Italian Version of the Quality of Life in Late-Stage Dementia (QUALID) Scale. J Alzheimers Dis 2:104e. doi:

Copyright: © 2012 De Vreese LP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Purpose: The aim of this study is to verify a cross-cultural adaptation of an Italian version of the Quality of Life in Late-Stage Dementia (QUALID) scale in a sample of aging people with intellectual disabilities (ID). Methods: The QUALID was translated according to standardized procedures. Internal consistency was analyzed using Cronbach?s alpha. A Principal Component Analysis verified its multidimensionality. Inter-rater and test-retest reliabilities were also assessed using the Intraclass Correlation Coefficient (ICC). Convergent validity was probed by Spearman?s correlations among the QUALID score and the six sub-scores of the Assessment for Adults with Development Disabilities (AADS), a proxy-based questionnaire rating behavioral excesses and deficits commonly found in people with intellectual disabilities and dementia. Clinical validity was assessed by comparing QUALID scores obtained by subjects with and without dementia using the Mann-Whitney U test. Results: A total of 40 adults/older people with ID at five ID-specific centers in the province of Trento and Cremona participated in the study. Findings show optimal levels of internal consistency (α = 0.80) and confirm the factors identified in the Spanish validation study (symptoms of discomfort, positive social interaction and depression). The scale has high inter-rater (ICC = 0.95) and good test-retest reliabilities (ICC = 0.89). The total QUALID score correlates significantly with the AADS sub-scores for behavioral excesses, but does not differ between individuals with and without dementia, though two out of the three identified factor scores are significantly higher in the dementia subgroup. Conclusions: The Italian version of the QUALID is a reliable and valid instrument for estimating quality of life in aging adults with ID and dementia.