Melanosis “Coli” in Anal Heterotopic Gastric Mucosa: A Case Report and Review of the Literature
Debbie R Walley*, Robert Greer, Maria F Gonzalez and Charu Subramony
Department of Pathology, University of Mississippi Medical Center, Hospital in Jackson, Mississippi, USA
- *Corresponding Author:
- Debbie R Walley
Department of Pathology
University of Mississippi Medical Center
Hospital in Jackson, Mississippi, USA
E-mail: [email protected]
Received date: September 7, 2016; Accepted date: September 24, 2016; Published date: September 29, 2016
Citation: Walley DR, Greer R, Gonzalez MF, Subramony C (2016) Melanosis “Coli” in Anal Heterotopic Gastric Mucosa: A Case Report and Review of the Literature. J Gastrointest Dig Syst 6:471. doi: 10.4172/2161-069X.1000471
Copyright: © 2016 Walley DR et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Gastric heterotopia is the presence of gastric mucosa in a foreign anatomic location. It can occur anywhere in the gastrointestinal tract and has been well documented in the esophagus. Gastric heterotopia of the anorectum is a rare occurrence.
Case Report: We present a case of an asymptomatic adult male who underwent a colonoscopy during which an anal nodule was biopsied. Microscopic examination revealed oxyntic gastric mucosa with chronic active gastritis and melanosis coli. During a subsequent colonoscopy six years later, an abnormally pigmented area of anus was biopsied. Microscopic examination revealed antral gastric mucosa with chronic active gastritis.
A literature review showed that there have been 72 reported cases of gastric heterotopia of the anorectum. Only four of those case occurred in the anus.
Conclusion: To our knowledge, this is the first report of melanosis coli associated with gastric heterotopia of the anorectum as well as a shift in gastric mucosal type on repeat biopsy. We propose the term "outlet patch" for gastric heterotopia of the anorectum.