Case Report
Mucinous Appendiceal Adenocarcinoma Presenting as Sister Mary Joseph Nodule: Case Report and Brief Review of Literature
Amareshwar Podugu, Alicia Alvarez, Ronnie Pimentel and Andrew Ukleja*
Digestive Disease Institute, Cleveland Clinic Florida, Weston, Florida, USA
- *Corresponding Author:
- Dr. Andrew Ukleja, MD
Department of Gastroenterology
2950 Cleveland Clinic Blvd, Weston
Florida 33331, USA
Tel: 954659-5646
E-mail: UKLEJAA@ccf.org
Received date: August 14, 2015 Accepted date: Sepember 14, 2015 Published date: Sepember 21, 2015
Citation: Podugu A, Alvarez A, Pimentel R, Ukleja A (2015) Mucinous Appendiceal Adenocarcinoma Presenting as Sister Mary Joseph Nodule: Case Report and Brief Review of Literature . J Gastrointest Dig Syst 5:339. doi:10.4172/2161-069X.1000339
Copyright: © 2015 Podugu A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Sister Mary Joseph nodule is a rare form of umbilical metastasis. Often, this is the only initial presenting sign for an underlying internal malignancy and is usually associated with poor prognosis. Although the gastrointestinal tract is the most common primary site, the majority of these metastases are from gastric and colorectal sites. We report a case of Sister Mary Joseph nodule in a patient with no GI complaints. Further evaluation led to the diagnosis of primary mucinous adenocarcinoma of the appendix. Primary mucinous adenocarcinoma of the appendix is a very rare tumor type that can give rise to umbilical metastases. To the best of our knowledge, only 3 cases of adenocarcinoma of the appendix metastasizing to the umbilicus have been reported in the medical literature.