Abstract

Neglected Tropical Diseases (NTDs) caused by parasitic infections continue to pose a major public health challenge, particularly in low- and middle-income countries. These diseases, including schistosomiasis, lymphatic filariasis, Chagas disease, leishmaniasis, and soil-transmitted helminth infections, affect millions of people, leading to chronic illness, disability, and socioeconomic burdens. Limited healthcare access, poor sanitation, and inadequate funding for research and treatment contribute to their persistence. Advances in diagnostic tools, mass drug administration programs, and novel vaccine development have improved disease control efforts. However, challenges such as drug resistance, environmental factors, and the need for sustainable intervention strategies remain. This review explores the epidemiology, impact, and current progress in the fight against parasitic NTDs, highlighting the importance of global collaboration and innovative approaches to achieving disease elimination.