alexa Neuroprotective Effect of Curcumin with a Fixator of Absorption against both Aluminium Neurotoxicity and Alzheimer's Disease (Experimental Studies in Mice) | Abstract
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Neuroprotective Effect of Curcumin with a Fixator of Absorption against both Aluminium Neurotoxicity and Alzheimer's Disease (Experimental Studies in Mice)

Salima Douichene1*, Noureddine Djebli1, Moussa Ahmed2 and Kheira Zerrouki1

1Department of Biology, Faculty of SE & SNV, Laboratory of Micro Biology and Vegetal Biology (LMVB), Mostaganem University, Mostaganem, Algeria

2Department of Biology, Faculty of Sciences, Tiaret University, Tiaret, Algeria

Corresponding Author:
Salima Douichene
Department of Biology, Faculty of SE & SNV
Laboratory of Micro Biology and Vegetal Biology (LMVB)
Mostaganem University, Mostaganem, Algeria
E-mail: [email protected]

Received date: June 13, 2012; Accepted date: August 10, 2012; Published date: August 13, 2012

Citation: Douichene S, Djebli N, Ahmed M, Zerrouki K (2012) Neuroprotective Effect of Curcumin with a Fixator of Absorption against both Aluminium Neurotoxicity and Alzheimer’s Disease (Experimental Studies in Mice). J Alzheimers Dis Parkinsonism 2:107. doi:10.4172/2161-0460.1000107

Copyright: © 2012 Douichene S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The versatility of Aluminium chemistry will ensure its burgeoning use in the future in all manner of applications. This very same chemistry will also ensure its increased biological availability in all biota including man. We do not know enough about the biological chemistry of a chronic and sub-acute exposure to Aluminium to be able to predict its impact on human health. Although the hypothesis of a link between Aluminium and Alzheimer's Disease (AD) has been supported by several epidemiological studies, there is much controversy regarding these findings and their interpretation. There is no doubt that the drugs discovered for neurodegenerative disease are far from ideal, and are not more than acetyl cholinesterase inhibitors, in fact alternative medicine could be moderate and protect nerves from neurotoxicity and AD. Curcumin is one of strong medicinal species that prove antioxidative stress effect against reactions cascade of neurofibrillary tangles. Our aims is to clarify the role of Curcumin with a fixative of absorption as a protective and therapeutic agent against neurodegenerative disorders and Alzheimer's disease induced by AlCl3 on the pyramidal cells in cerebral cortex and hippocampus of albino mice, by means of two experiences realized with a different exposition of albino mice; sub acute and chronic exposure with a different manner (PO and IP) on Curcumin with a fixative of absorption and AlCl3.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7