New Endoscopic Diagnosis and Treatment Options for Early Esophageal Cancer | OMICS International | Abstract
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

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Review Article

New Endoscopic Diagnosis and Treatment Options for Early Esophageal Cancer

Quan-Lin Li, Yun-Shi Zhong, Wei-Feng Chen, Meng-Jiang He, Ping-Hong Zhou and Li-Qing Yao*

Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, People’s Republic of China

*Corresponding Author:
Li-Qing Yao
Endoscopy Center and Endoscopy Research Institute
Zhongshan Hospital, Fudan University
180 Fenglin Road, Shanghai 200032
People’s Republic of China
E-mail: [email protected]

Received date: September 29, 2011; Accepted date: April 05, 2012; Published date: April 07, 2012

Citation: Li QL, Zhong YS, Chen WF, He MJ, Zhou PH, et al. (2012) New Endoscopic Diagnosis and Treatment Options for Early Esophageal Cancer. J Gastroint Dig Syst 2:108. doi: 10.4172/2161-069X.1000108

Copyright: © 2012 Li QL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Recent advances in endoscopic technology have increased detection rates of early esophageal cancer. Novel imaging techniques, such as narrow band imaging, autofluorescence imaging, confocal laser endomicroscopy and optical coherence tomography, have been recently introduced that may be taking us closer to the “optical biopsy” for dignosis of esophageal lesions. Along with the increased endoscopic detection rates, more and more early esophageal lesions have been also treated by endoscopic options. There are now long-term randomized controlled data concerning the effectiveness of ablative approaches (photodynamic therapy, cryotherapy and radiofrequency ablation); however, the ablation does not provide a tissue specimen for histopathological assessment. Unlike ablative techniques, endoscopic resection permits histopathological assessment, similar to surgery. As a new resection technique, endoscopic submucosal dissection results in complete eradication of all diseases and may translate to a lower recurrence rate than conventional endoscopic mucosal resection procedure.