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Oropharyngolaryngeal Sarcocystosis and Histoplasmosis Co-Infection in a Patient with Systemic Lupus Erythematosus | OMICS International| Abstract
ISSN: 2476-2024

Diagnostic Pathology: Open Access
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  • Case Report   
  • Diagn Pathol Open 2016, Vol 1(3): 117
  • DOI: 10.4172/2476-2024.1000117

Oropharyngolaryngeal Sarcocystosis and Histoplasmosis Co-Infection in a Patient with Systemic Lupus Erythematosus

Noppadol Larbcharoensub1*, Wasana Kanoksilp1, Chewarat Wirojtananugoon2, Maria Nina Chitasombat3, Wannapong Chawengkiattikul3, Kanyaprin Bhummichitra4 and Prawat Nitiyanant1
1Department of Pathology, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand
2Department of Radiology, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand
3Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand
4Division of Anatomical Pathology, Surat Thani Hospital, , Surat Thani, 84000, Thailand
*Corresponding Author : Noppadol Larbcharoensub, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi, Bangkok 10400, Thailand, Tel: +66-0-2354-7277, Fax: +66-0-2354 7266, Email: [email protected]

Received Date: Jun 30, 2016 / Accepted Date: Jul 20, 2016 / Published Date: Jul 22, 2016

Abstract

Sarcocystosis is an uncommon zoonotic coccidian protozoal infection caused by Sarcocystis spp. Muscular sarcocystosis have been detected in patients with various types of cancer but co-infection with histoplasmosis has never been reported. We report a 39-year-old woman with active lupus nephritis who presented with hoarseness for eleven months. Physical examination and magnetic resonance imaging revealed an irregular exophytic mass at the left oropharynx and the left true vocal cord. The histopathologic diagnosis was oropharyngolaryngeal sarcocystosis and histoplasmosis. She was treated with oral itraconazole for histoplasmosis. The authors briefly review the clinicopathologic features and pathogenesis of oropharyngolaryngeal sarcocystosis and histoplasmosis and conclude the possibility of co-infection of oropharyngolaryngeal sarcocystosis and histoplasmosis, especially in immunocompromised patient.

Keywords: Sarcocystosis; Histoplasmosis; Systemic lupus erythematosus; Larynx; Oropharynx

Citation: Larbcharoensub N, Kanoksilp W, Wirojtananugoon C, Chitasombat MN, Chawengkiattikul W, et al. (2016) Oropharyngolaryngeal Sarcocystosis and Histoplasmosis Co-Infection in a Patient with Systemic Lupus Erythematosus. Diagn Pathol Open 1: 117. Doi: 10.4172/2476-2024.1000117

Copyright: ©2016 Larbcharoensub N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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