Osteogenesis Imperfecta and Constipation: A Case Report
Marwa Abu El Haija*
Pediatrics, PGY-1, University of Texas Medical Branch-Galveston, Texas, USA
- *Corresponding Author:
- Marwa Abu El Haija
University of Texas Medical Branch-Galveston, Texas, USA
E-mail: [email protected]
Received date: January 19, 2013; Accepted date: February 16, 2013; Published date: February 18, 2013
Citation: El Haija MA (2013) Osteogenesis Imperfecta and Constipation: A Case Report. J Gastroint Dig Syst S3:003. doi: 10.4172/2161-069X.S3-003
Copyright: © 2013 El Haija MA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Osteogenesis imperfecta (OI) is a heterogeneous group of heritable group of disorders in which the amount of type-1 collagen is decreased or the type 1 collagen is abnormal . 90% of cases are due to autosomal dominant mutations, while the remaining 10% are due to autosomal recessive mutations or of unknown cause. Type III was found to be associated with chronic gastrointestinal (GI) problems including constipation. There are two studies that showed that children and adults who have OI Type III are more likely to have constipation and complaints of abdominal pain, constipation was contributed to pelvic deformities in those reports. We present a case of an 18 year- old female with chronic constipation and that was found to have Hirschsprung’s disease.