Perineural Invasion of Skin Cancers in the Head and Neck: An Uncommon Phenomenon Revisited*Corresponding Author: Santhosh Gaddikeri MD, Department of Radiology, University of Washington Medical Center, 1959 NE Pacific Street, Box 357115, Seattle, WA- 98195-7115, USA, Tel: 206-598-5130, Fax: 206-598-8475, Email: [email protected]
Received Date: Mar 19, 2014 / Accepted Date: Apr 04, 2014 / Published Date: Apr 11, 2014
Citation: Gaddikeri S, Bhrany A, Anzai Y (2014) Perineural Invasion of Skin Cancers in the Head and Neck: An Uncommon Phenomenon Revisited. Otolaryngology 4:169.DOI: 10.4172/2161-119X.1000169
Copyright: © 2014 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The purpose of this article is to describe the epidemiology, imaging findings, pathogenesis, and clinical impact of perineural invasion of skin cancers in the head and neck.
Conclusion: Perineural invasion in head and neck skin cancer can be microscopic disease discovered on pathology or gross perineural spread that can be predicted on imaging often accompanied with clinical symptoms. Physicians and radiologists should have high index of suspicion when evaluating with patient with skin cancer that is in close proximity to a cranial nerve. The advancement of imaging techniques has improved pre-operative detection of perineural invasion of skin cancer.