Perineural Invasion of Skin Cancers in the Head and Neck: An Uncommon Phenomenon RevisitedSanthosh Gaddikeri1*, Amit Bhrany2 and Yoshimi Anzai1
- Corresponding Author:
- Santhosh Gaddikeri MD
Department of Radiology
University of Washington Medical Center
1959 NE Pacific Street, Box 357115
Seattle, WA- 98195-7115, USA
E-mail: [email protected]
Received date: March 19, 2014; Accepted date: April 04, 2014; Published date: April 11, 2014
Citation: Gaddikeri S, Bhrany A, Anzai Y (2014) Perineural Invasion of Skin Cancers in the Head and Neck: An Uncommon Phenomenon Revisited. Otolaryngology 4:169. doi:10.4172/2161-119X.1000169
Copyright: © 2014 Gaddikeri S et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The purpose of this article is to describe the epidemiology, imaging findings, pathogenesis, and clinical impact of perineural invasion of skin cancers in the head and neck.
Conclusion: Perineural invasion in head and neck skin cancer can be microscopic disease discovered on pathology or gross perineural spread that can be predicted on imaging often accompanied with clinical symptoms. Physicians and radiologists should have high index of suspicion when evaluating with patient with skin cancer that is in close proximity to a cranial nerve. The advancement of imaging techniques has improved pre-operative detection of perineural invasion of skin cancer.