Periodontal Intrabony Defects and the Treatment with Enamel Matrix Derivative and a Synthetic Bone Substitute in Humans: A Clinical and Radiographic Case SeriesPatricia Garani Fernandes1,2, Idiberto José Zotarelli Filho3, Gustavo Henrique Apolinário Vieira1, Arthur B. Novaes Jr1, Sergio Luís Scombatti de Souza4, Mario Taba Jr4, Daniela Bazan Palioto4 and Márcio Fernando de Moraes Grisi4*
- Corresponding Author:
- Márcio Fernando de Moraes Grisi
Department of Oral Surgery and Periodontology
Ribeirão Preto School of Dentistry
University of São Paulo
Avenida do Café - s/n, 14040-904
Ribeirão Preto, SP, Brazil
E-mail: [email protected]
Received date: July 20, 2015; Accepted date: August 13, 2015; Published date: August 18, 2015
Citation: Fernandes PG, Zotarelli Filho IJ, Apolinário Vieira GH, Novaes Jr AB, Scombatti de Souza SL, et al. (2015) Periodontal Intrabony Defects and the Treatment with Enamel Matrix Derivative and a Synthetic Bone Substitute in Humans: A Clinical and Radiographic Case Series. J Interdiscipl Med Dent Sci 3:185. doi: 10.4172/2376-032X.1000185
Copyright: © 2015 Fernandes PG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The aim of this study was to analyze by clinical and radiographic parameters the use of enamel matrix derivative (EMD) with or without a synthetic bone substitute (Bone Ceramic) in the treatment of periodontal intrabony defects in humans.
Methods: Nine patients and eighteen defects in need of treatment for periodontal intrabony defects were selected and assigned to the treatment with EMD or EMD plus Bone Ceramic assessing clinical and radiographic measurements.
Results: At one year, mean probing depth (PD) reduction demonstrated improvements in all groups when compared to the baseline (P<0.01). At 1 year PD reduction ≥ 2mm was measured in 57% of the defects (i.e., in 4 of the 7) when EMD + BC was used; in 36% of the defects (i.e., 4 of the 11) when EMD was used. There were no statistically significant differences when standardized radiographic subtractions were compared radiographic.
Conclusion: In conclusion, results from the present cases series confirm that a regenerative procedure based on EMD plus Bone Ceramic had better results in defect fill, although there was a variation in the numbers of defects.