Peritoneal Mesothelioma and Asbestos: Clarifying the Relationship by Epidemiology
Marty S. Kanarek* and Madalyn K. Mandich
Department of Population Health Sciences, School of Medicine and Public Health and the Nelson Institute for Environmental Studies, University of Wisconsin-Madison, USA
- Corresponding Author:
- Marty S. Kanarek
Department of Population Health Sciences
School of Medicine and Public Health
610 N. Walnut Street
University of Wisconsin-Madison, USA
E-mail: [email protected]
Received date: February 24, 2016; Accepted date: March 23, 2016; Published date: March 29, 2016
Citation: Kanarek MS, Mandich MK (2016) Peritoneal Mesothelioma and Asbestos: Clarifying the Relationship by Epidemiology. Epidemiology (Sunnyvale) 6:233. doi:10.4172/2161-1165.1000233
Copyright: © 2016 Kanarek MS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Peritoneal mesothelioma has been recognized for over a half century, but causality with asbestos of different fiber types and the incidence of this fatal tumor in relation to asbestos exposure dose still needs clarification. In order to help bring clarity, the most important studies on peritoneal mesothelioma, including a brief history, relationship to asbestos exposures, diagnostic issues and experimental studies are reviewed including case series, case-control, occupational, and registry epidemiology studies. This review concludes that all types of asbestos, including amphiboles and chrysotile, are causative for peritoneal mesothelioma. Many cases have been found in both males and females from asbestos exposures in occupational and neighborhood settings, shown in differing epidemiology study designs. It is clear that there is a causal relationship between all types of asbestos at all dose levels for peritoneal mesothelioma and no threshold of exposure to asbestos appears safe.