Poly (<em>N</em>-Isopropylacrylamide) Microgel-Based Etalons for Optical Sensing | OMICS International | Abstract
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

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Review Article

Poly (N-Isopropylacrylamide) Microgel-Based Etalons for Optical Sensing

Liang Hu and Michael J. Serpe*
Department of Chemistry, University of Alberta, Edmonton, AB, T6G2G2 Canada
Corresponding Author : Michael J. Serpe
Department of Chemistry, University of Alberta
Edmonton, AB, T6G2G2 Canada
E-mail: [email protected]
Received April 07, 2012; Accepted May 05, 2012; Published May 09, 2012
Citation: Hu L, Serpe MJ (2012) Poly (N-Isopropylacrylamide) Microgel-Based Etalons for Optical Sensing. J Anal Bioanal Tech 3:132. doi: 10.4172/2155-9872.1000132
Copyright: © 2012 Hu L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Poly (N-isopropylacrylamide) (pNIPAm) is one of the most completely studied “smart” polymers due to its unique reversible thermoresponsivity. That is, when pNIPAm in water is heated > ~31°C, it transits from a random coil to a globule conformation; this transition is reversed when T < ~31°C. This conformational change is accompanied by water exchange process. When pNIPAm undergoes the coil to globule transition, water is expelled, while water is “sorbed” when the polymer undergoes the opposite process.