alexa Protocol for Three Dimensional Histopathological Examin
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

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Case Report

Protocol for Three Dimensional Histopathological Examination of the Vermiform Appendix in Neuroendocrine Tumors

Samir Ghani* and Pradeep Hamal

Frimley Health NHS Foundation Trust, Slough, Berkshire, United Kingdom

Corresponding Author:
Samir Ghani
Associate Specialist, Frimley Health NHS Foundation Trust Pathology
Wexham Road, Slough, Berkshire SL2 4HL United Kingdom
Tel: 044-07956716461
E-mail: [email protected]

Received Date: January 27, 2016 Accepted Date: March 1, 2016 Published Date: March 9, 2016

Citation:Ghani S, Hamal P (2016) Protocol for Three Dimensional Histopathological Examination of the Vermiform Appendix in Neuroendocrine Tumors. J Gastrointest Dig Syst 6:394. doi:10.4172/2161-069X.1000397

Copyright: © 2016 Ghani S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The conventional protocol for dissection of the vermiform appendix in the Surgical Pathology laboratory allows two dimensional (2-D) histopathological examination of the tip of the appendix. In this report, a new three dimensional (3-D) approach is described, to allow thorough (360 degree) histopathological examination of the entire serosal surface and muscular wall of the tip of the appendix. This is designed to deal with neuroendocrine (NE) tumors that may present at this anatomical location as a routine daily case in every histopathology department. To our knowledge, this approach has not been described in the literature of NE tumors of the appendix.


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