Red Blood Cell Distribution Width as an Old and New Marker in Various Vascular Diseases
Nishiyama Y* and Ikeda H
Department of Cardiology, Kurume University Medical Center, Japan
- *Corresponding Author:
- Nishiyama Y
Department of Cardiology, Kurume University Medical Center
155-1 Kokubu-machi, Kurume, 839-0863, Japan
E-mail: [email protected]
Received date: April 21, 2017; Accepted date: May 8, 2017; Published date: May 11, 2017
Citation: Nishiyama Y, Ikeda H (2017) Red Blood Cell Distribution Width as an Old and New Marker in Various Vascular Diseases. J Card Pulm Rehabil 1:104.
Copyright: © 2017 Nishiyama Y et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Red blood cell distribution width (RDW) is the quantitative measure of anisocytosis showing the variability in size of the circulating erythrocytes. Generally, higher RDW reflects increased red blood cell destruction such as hemolytic disorders and nutritional deficiency including iron, vitamin B12 and folate deficiency. Recently, several studies showed a strong independent association between higher RDW and the poor prognosis in various vascular diseases such as heart, brain and kidney. This review will refer the underlying mechanisms of the beneficial prognostic marker of RDW in those diseases.