Salivary IgA and Dental Caries in Type II Diabetics in Indian Adult Population
Mithra N Hegde*, Fayaz Gafoor, Darshana Devadiga, Divya Tahiliani and Chittaranjan Shetty
Department of Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences, Nitte University, Deralakatte, Mangalore, Karnataka, India
- Corresponding Author:
- Mithra N. Hegde
Senior Professor and Head of the Department
Department of Conservative Dentistry and Endodontics
AB Shetty Memorial Institute of Dental Sciences
Nitte University, Deralakatte, Mangalore, Karnataka, India
Received date: April 11, 2014; Accepted date: June 30, 2014; Published date: July 7, 2014
Citation: Hegde MN, Gafoor F, Devadiga D, Tahiliani D, Shetty C (2014) Salivary IgA and Dental Caries in Type II Diabetics in Indian Adult Population. J Interdiscipl Med Dent Sci 2:133. doi:10.4172/2376-032X.1000133
Copyright: © 2014 Hegde, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Aim: To evaluate relationship between Salivary IgA and Dental caries in Type II Diabetics in Indian Adult Population.
Method: Study was conducted on 30 patients of age group ranging from 25-60years including type II diabetic and non diabetic patients. Patients were divided into 3 groups of 10 subjects each according to diabetic and DMFT scores as G-1 (control, non diabetic) DMFT- 0, G-2 (non diabetic) DMFT 4 - 8 and G-3 (diabetic) DMFT 4 - 8. Unstimulated saliva samples were collected from each subject for estimation of IgA using the Turbidometric method. Data obtained were statistically analysed.
Results: Correlation of Salivary IgA and DMFT showed steady decrease in values of Salivary-IgA from Group I – III. The variation in Salivary- IgA level was Very Highly Significant [VHS] when diabetic DMFT 4-8 was compared with control and non diabetic DMFT 4-8; Highly significant [HS] between control and non diabetic DMFT 4-8.
Conclusion: Salivary-IgA values showed an inverse relationship to the DMFT values with levels of Salivary-IgA decreasing with an increase in DMFT Values. Salivary-IgA level in type II Diabetic patients with DMFT-4-8 had significantly lower values than non diabetic patients of similar DMFT scores.