alexa Skin ultrastructural similarities between Fibromyalgia and Ehlers-Danlos syndrome hypermobility type | OMICS International | Abstract

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Short Communication

Skin ultrastructural similarities between Fibromyalgia and Ehlers-Danlos syndrome hypermobility type

Hermanns-Lê T1* and Pierard GE2

1Unit of electron microscopy, Department of Pathology, Unilab LG, University Hospital, Liège, Belgium

2Laboratory of Skin Bioengineering and Imaging (LABIC), Department of Clinical Sciences, Liège University, Belgium

*Corresponding Author:
Pierard GE
Laboratory of Skin Bioengineering and Imaging (LABIC)
Department of Clinical Sciences
Liège University, Belgium
Email: [email protected]

Received date: December 04, 2015; Accepted date: December 15, 2015; Published date: January 27, 2016

Citation: Hermanns-Le T and Pierard GE (2016) Skin Ultrastructural similarities between Fibromyalgia and Ehlers-Danlos Syndrome Hypermobility Type. J Ost Arth 1:104. doi: 10.4172/joas.1000104

Copyright: © 2016 Hermanns-Lê T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Fibromyalgia (FM) and hypermobility type Ehlers-Danlos syndrome (EDSH) share a series of common clinical signs. A clinical distinction between both diseases is occasionally difficult to be established. The physical changes observed in the mechanical properties of skin and joints do not distinctly distinguish these disorders. In addition, similar ultrastructural dermal changes are observed in both EDSH and some FM cases. The molecular alterations remain largely undisclosed in both diseases. As a result, EDSH remains undiagnosed in some FM patients. This condition deteriorates quality of life and possibly leads to prominent health problems.