alexa Statins in Cirrhotic Portal Hypertension – A Brief Review | OMICS International| Abstract
ISSN: 2471-9919

Evidence based Medicine and Practice
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  • Review Article   
  • Evid Based Med Pract,
  • DOI: 10.4172/2471-9919.1000110

Statins in Cirrhotic Portal Hypertension – A Brief Review

Pollo-Flores P1* and Leonardo Roever2
1Department of Internal Medicine, Fluminense Federal University, Rio de Janeiro, Brazil
2Department of Clinical Research, Federal University of Uberlandia, Uberlândia, Brazil
*Corresponding Author : Pollo-Flores P, Internal Medicine, Fluminense Federal University, Rio De Janeiro, Brazil, Tel: + 55(21) 98777-7011, Email: [email protected]

Received Date: Oct 20, 2016 / Accepted Date: Nov 21, 2016 / Published Date: Nov 28, 2016

Abstract

Nowadays the cirrhosis physiopatology is being deeply studied and new pharmacology approach comes with new perspective of changing natural history and initial steps of the disease. The statins have many properties in this sense. These drugs have demonstrated effects improving portal hypertension, liver functions, hepatocellular carcinoma with few side effects. Its action mechanism happens predominantly in intrahepatic environment, what seems very attractive. Some studies were conducted in animals and very few in human beings. This brief review aim to address advantages of the use of statins in liver disease. One question still open is which statin is the best in liver disease and which population of cirrhotic profit the most of the drug.

Keywords: Portal hypertension; Statins; Cirrhosis

Citation: Pollo-Flores P, Roever L (2016) Statins in Cirrhotic Portal Hypertension – A Brief Review. Evid Based Med Pract 2: 110. Doi: 10.4172/2471-9919.1000110

Copyright: ©2016 Pollo-Flores P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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