Abstract

High-Performance Liquid Chromatography (HPLC) has transformed pharmaceutical analysis by enabling precise and efficient simultaneous estimation of multiple drugs in complex mixtures, offering advantages such as time efficiency and high precision. However, challenges like ensuring selectivity and rigorous method validation persist. Meanwhile, cardiovascular diseases remain a global health concern, necessitating optimized analytical methods for cardiovascular drugs. This study aims to develop advanced techniques tailored to cardiovascular drug complexities, addressing challenges like formulation variations and regulatory compliance. By optimizing methods and ensuring regulatory adherence, this research contributes to enhancing pharmaceutical analysis in cardiovascular care. Through rigorous method development and validation, this study seeks to advance the field, ultimately improving patient outcomes in cardiovascular disease management.