Journal of Gastrointestinal & Digestive System
Open Access

Research Article

The Risk of Ileocolonic Perforation in Patients with Behet's Disease: Report of Three Cases and Review of the Literature

¹Ankara University School of Medicine, Department of Gastroenterology, Ankara-Turkey

²Ankara University School of Medicine, Department of Dermatology, Ankara- Turkey

³Ankara University School of Medicine, Department of Pathology, Ankara-Turkey

⁴Ankara University School of Medicine, Department of Surgery, Ankara-Turkey

*Corresponding Author:

Mehmet Bektas
Ankara University School of Medicine
Department of Gastroenterology, Ibn-iSina Hospital
Sihhiye, Ankara-Turkey 06100
Tel: +903125082150
Fax: +90 312 363 6213
E-mail: mbektas@medicine.ankara.edu.tr

Received date: March 22, 2014; Accepted date: April 25, 2014; Published date: April 30, 2014

Citation: Bektas M, Kalkan C, Soykan I, Boyvat A and Savas B, et al., (2014) The Risk of Ileocolonic Perforation in Patients with Behçet's Disease: Report of Three Cases and Review of the Literature. J Gastroint Dig Syst 4:184. doi:10.4172/2161-069X.1000184

Copyright: © 2014 Bektas M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Introduction/Purpose: Intestinal Behcet’s disease may cause serious complications. Massive hemorrhage, fistulisation and intestinal perforation are encountered complications in approximately 50% of patients suffering from intestinal Behcet’s disease. Currently, there is not enough data inquiring iatrogenic ileocolonic perforation during colonoscopy in patients with intestinal Behcet’s disease; therefore we aimed to study intestinal Behcet’s disease patients who suffered perforation during or after colonoscopy. Methods: A total of 2615 colonoscopic examinations were performed between May 2002 and December 2007. Of these 2615 patients, main indication for colonoscopy was intestinal Behcet’s disease in 135 patients. Results: In total 135 patients with Behcet’s patients were assessed with colonoscopy due to presumed ileocolonic involvement. 8 out of 135 (5.9%) patients had ileal and colonic ulcers. 3 patients (2.22%) had iatrogenic perforation, 2 of whom had profound ulcers in proximal colon and ileum. The third case had ulcers in sigmoid colon, descending and transverse colon segments. All these 3 patients had undergone surgical intervention including ileal resection and right hemicolectomy. Discussion: Colonoscopic examination is commonly used in Behcet’s disease not only for diagnostic purposes but also for surveillance of intestinal involvement in Behcet’s disease. Volcano-shaped ulcers are specially inclined to perforate. Both clinicians and endoscopists should be alert against barotrauma applied during colonoscopy may cause perforation. Also patients should be followed-up necessarily and in case of abdominal pain after colonoscopic examination, colonic perforation should always be kept in mind.f

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