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  • Research Article   
  • Arch Parasitol 2017, Vol 1(2): 111

Therapeutic Efficacy of Closantel Against Different Gastrointestinal Parasites in Sheep

Sivajothi S1 and Sudhakara Reddy B2*
1Department of Veterinary Parasitology, College of Veterinary Science, Sri Venkateswara Veterinary University, Proddatur - 516360, Andhra Pradesh, India
2Department of Veterinary Medicine, College of Veterinary Science, Sri Venkateswara Veterinary University, Proddatur - 516360, Andhra Pradesh, India
*Corresponding Author : Sudhakara Reddy B, Department of Veterinary Medicine, College of Veterinary Science, Sri Venkateswara Veterinary University, Proddatur - 516360, Andhra Pradesh, India, Tel: 9030218657, Email: bhavanamvet@gmail.com

Received Date: Aug 01, 2017 / Accepted Date: Aug 21, 2017 / Published Date: Aug 28, 2017

Abstract

Small ruminants are suffered by many numbers of health issues mainly gastro intestinal parasites. These conditions can be controlled and treated with different chemotherapeutic regimens. The present study was conducted in YSR Kadapa district of Andhra Pradesh in 2016. Thirty sheep were selected randomly from three different flocks and were treated with oral administration of closantel at 10 mg/kg body weight. Before treatment and 1st, 7th, 14th and 21st day of post treatment faecal samples were collected for determination of parasitic intensity by analysis of egg per gram of faeces. Therapeutic efficacy of the drug against different gastrointestinal parasites was carried out by the percentage reduction in the egg per gram levels. It was highly effective against Strongyloides spp., Haemonchus contortus, Oesophagostomum spp., Trichuris spp., Fasciola gigantica and Paramphistome spp.. Reduction in the intensity of parasitic ova was 25.5%, 90.6%, 98.2% and 99.5% by the 1st day, 7th day, 14th day and 21st day of post treatmentrespectively. In conclusion, higher efficacy of closantel was observed against the different gastro intestinal trematodes and nematodes in the present geographical location.

Keywords: Closantel; Sheep; Gastrointestinal parasites; India

Citation: Sivajothi S, Sudhakara Reddy B (2017) Therapeutic Efficacy of Closantel Against Different Gastrointestinal Parasites in Sheep. Arch Parasitol 1:111.

Copyright: © 2017 Sivajothi S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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