Utilizing Dehydrated Human Amnion/Chorion Membrane Allograft in Transcanal Tympanoplasty
Received Date: Jan 23, 2014 / Accepted Date: Feb 22, 2014 / Published Date: Mar 02, 2014
Objective: To evaluate the utility and effectiveness of dehydrated Human Amnion/Chorion Membrane (dHACM) in transcanal tympanoplasty.
Patients: A retrospective analysis of 14 patients (8 adults and 4 children) with stable tympanic membrane perforations for greater than 6 months.
Intervention: Transcanal tympanoplasty performed by a single surgeon utilizing a dHACM allograft.
Main outcome measures: Operative time, pain, graft success and audiologic improvement.
Results: At the 6 week post-operative visit a decrease in perforation size was noted in 8 patients (57.1%) and complete closure of the perforation occurred in 6 (42.9%). For patients without tympanosclerosis (n=10) complete closure was achieved in 5 patients (50%) and complete or partial success in 7 patients (70%). Mean air bone gap decreased from a pre-operative measurement of 23.0 ± 10.1 dB to 16.8 ± 7.4 dB at 6 weeks after tympanoplasty. The technique was well tolerated. Using the transcanal method and dehydrated amnion/chorion membrane allograft, the mean operative time was 13.3 ± 0.10 minutes.
Conclusions: Commercially available dHACM appears to be a safe, viable graft material for transcanal tympanoplasty.
Keywords: Allograft, Amniotic membrane, Tympanoplasty
Citation: Hsu GS (2014) Utilizing Dehydrated Human Amnion/Chorion Membrane Allograft in Transcanal Tympanoplasty. Otolaryngology 4:161. Doi: 10.4172/2161-119X.1000161
Copyright: © 2014 Hsu GS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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