alexa Utilizing Dehydrated Human Amnion/Chorion Membrane Allograft in Transcanal Tympanoplasty | OMICS International | Abstract
ISSN: 2161-119X

Otolaryngology: Open Access
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Research Article

Utilizing Dehydrated Human Amnion/Chorion Membrane Allograft in Transcanal Tympanoplasty

Griffith S Hsu*

DuPage Medical Group, Department of Otolaryngology-Head and Neck Surgery, Illinois, USA

Corresponding Author:
Griffith S Hsu
DuPage Medical Group
430 Pennsylvania Avenue
Suite 330, Glen Ellyn, IL 60137, USA
Tel: 6305457576
Fax: 6305457839
E-mail: [email protected]

Received date: January 23, 2014; Accepted date: February 22, 2014; Published date: March 02, 2014

Citation: Hsu GS (2014) Utilizing Dehydrated Human Amnion/Chorion Membrane Allograft in Transcanal Tympanoplasty. Otolaryngology 4:161. doi:10.4172/2161-119X.1000161

Copyright: © 2014 Hsu GS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objective: To evaluate the utility and effectiveness of dehydrated Human Amnion/Chorion Membrane (dHACM) in transcanal tympanoplasty.

Patients: A retrospective analysis of 14 patients (8 adults and 4 children) with stable tympanic membrane perforations for greater than 6 months.

Intervention: Transcanal tympanoplasty performed by a single surgeon utilizing a dHACM allograft.

Main outcome measures: Operative time, pain, graft success and audiologic improvement.

Results: At the 6 week post-operative visit a decrease in perforation size was noted in 8 patients (57.1%) and complete closure of the perforation occurred in 6 (42.9%). For patients without tympanosclerosis (n=10) complete closure was achieved in 5 patients (50%) and complete or partial success in 7 patients (70%). Mean air bone gap decreased from a pre-operative measurement of 23.0 ± 10.1 dB to 16.8 ± 7.4 dB at 6 weeks after tympanoplasty. The technique was well tolerated. Using the transcanal method and dehydrated amnion/chorion membrane allograft, the mean operative time was 13.3 ± 0.10 minutes.

Conclusions: Commercially available dHACM appears to be a safe, viable graft material for transcanal tympanoplasty.


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