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The Role of Neutrophil Extracellular Traps in Infectious Diseases
Seki M*
Division of Infectious Diseases and Infection Control, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, Japan
- *Corresponding Author:
- Masafumi Seki
Division of Infectious Diseases and Infection Control
Tohoku Medical and Pharmaceutical University Hospital
1-12-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8612, Japan
Tel: +81-22-983-1221
Fax: +81-22-983-1232
E-mail: seki@hosp.tohoku-mpu.ac.jp
Received date: June 02, 2017; Accepted date: June 15, 2017; Published date: June 17, 2017
Citation: Seki M (2017) The Role of Neutrophil Extracellular Traps in Infectious Diseases. J Infect Dis Ther 5:321. doi: 10.4172/2332-0877.1000321
Copyright: © 2017 Seki M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Neutrophils were recently thought as a key player of the innate immune response, and one of the defense mechanisms of these cells: Neutrophil extracellular traps (NETs) whereby they capture pathogens by actively releasing their nuclear contents into the extracellular space, were found in various infectious diseases. NETs are one of the major antimicrobial strategies, but extent and excessive activation of neutrophils may make collateral tissue damage.
