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Dr. Downer’s research interest is in neuroimmunology, with emphasis on the role of the innate immune system in neuroinflammatory conditions. He has a particular interest in Multiple Sclerosis (MS), and is interested in developing novel biomarkers that correlate with disease progression, in addition to assessing new therapeutic avenues in MS. He also has a particular interest in the cannabinoid system, and its role in regulating neuroinflammation. His research in this field has made significant contributions to our understanding of cannabinoids as anti-inflammatory therapies, particularly in MS.